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Watch Closely (1)crofelemer boosts amounts of pazopanib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch. Crofelemer has the possible to inhibit CYP3A4 at concentrations predicted within the gut; unlikely to inhibit systemically for the reason that minimally absorbed.A lot less than 95% adherence to nonnucleoside reverse-
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